Prof. Dr. Lilyana Angelov

Lilyana Angelov, MD

President, WScS

Head of tumor section Cleveland Clinic – Ohio, USA

Personal Information
Education
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University of Toronto, Ontario, Canada

 

Honors B. Sc.

1983-1987

 

University of Toronto, Ontario, Canada

Graduate Student, Department of Immunology

1987-1988

 

University of Toronto, Ontario, Canada

M.D.

1988-1992

 

Post-Graduate Training
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St. Michael’s Hospital, Ontario, Canada

 

Intern, Comprehensive Medical Team

1992-1993

 

University of Toronto, Ontario, Canada

Neurosurgical Resident, Division of Neurosurgery

1993-2001

 

St Michael’s Hospital, University of Toronto

General Neurosurgical/Trauma Fellowship

2001-2002

 

Cleveland Clinic, Cleveland , OH

Neuro-Oncology and Gamma Knife Fellowship

2002-2003

Institution/Institute/Department: Cleveland Clinic

 

Neurological Institute

Rose Ella Burkhardt Brain Tumor & Neuro-Oncology Center

 

Office Address: 9500 Euclid Avenue
Office Mail Code: S73
Office Phone: 216-444-4253
Beeper: 800-223-2273, Beeper: 29577
 Office E-mail: angelol@ccf.org
Facsimile: 216-444-0924
 

 

Professional Appointments (list recent to oldest)

Position/Rank: Staff Neurosurgeon
Institution/Institute/Department: Cleveland Clinic

 

Neurological Institute

Rose Ella Burkhardt Brain Tumor & Neuro-Oncology Center

Dates: 2003-Present
 

 

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Director, Neurosurgical Oncology Fellowship Program

Cleveland Clinic, Neurological Institute

Rose Ella Burkhardt Brain Tumor & Neuro-Oncology Center 2011-Present

 

Staff , Gamma Knife Center

Cleveland Clinic

2003-Present

 

Staff, Center for Spine Health

Cleveland Clinic

2006-Present

 

Director, Brain Tumor & Neuro-Oncology Center Primary

CNS Lymphoma Program

Cleveland Clinic

2005-Present

 

Head, Section of Spine Radiosurgery

Cleveland Clinic

2006-Present

 

Head, Section of Spine Tumors

Cleveland Clinic

2007-Present

 

Director, Blood Brain Barrier Disruption Program

Lakewood Hospital

2003-2007

 

Associate Staff

Lakewood Hospital

2003-2010

 

Courtesy Staff

Fairview Hospital

2003-2010

 

Courtesy Staff

Lutheran Hospital

2003-2007

 

 

Academic Appointments (list recent to oldest)
Position/Rank: Visiting Professor Appointment
Institution/Institute/Department: Cleveland Clinic Lerner College of Medicine
Dates: August 2010-Present
   
   
   
Certification and Licensure
Name of Board: State Medical Board of Ohio
Date of Certificate: 7/1/2013 – 7/1/2015
Licensure State/Number: 81630
   
Name of Board: College of Physicians and Surgeons
Date of Certificate: 5/31/2013 – 5/31/2014
Licensure State/Number: 65447
   
Name of Board: Fellow Royal College of Physicians and Surgeons of Canada
Date of Certificate: June 2001 – Present
Licensure State/Number 484561
   
  Board Certified, American Board of Neurological Surgeons
  March 2001 – Present
  Diplomate May 2007

 

Honors and Awards

Government Bursary for French Immersion Program, Nova Scotia: Summers 1984 & 1985

Summer Student Stipend from Ludwig Institute for Cancer Research, Toronto, Ontario: Summers 1986 & 1987

University of Toronto Open Scholarship for Graduate Studies, Toronto, Ontario: Summer 1989

Summer Scholarship, Institute of JMedical Sciences, Toronto, Ontario: Summer 1989

Dr. C.S. Wainwright Memorial Scholarship: Summer 1990

Leukemia Research Fund Scholarship to study at the Royal Post-Graduate Medical School, London, England: Summer 1991

National Cancer Institute (NCI) Canada Post-MD Research Fellowship-3 years: July 1997 – June 2000

American Association of Neurological Surgeons Research Fellowship – 2 years: July 1997-June 1999

Thomas P. Morley Neurosurgery Prize: February 1999

Gallie Bateman Postgraduate Surgery Finalist: May 1999

Mckenzie Award for Basic Neuroscience Research awarded by the Canadian Congress of Neurological Sciences: June 1999

Outstanding Oral Presentation Award at Neurosurgery + Science + Management Meeting New Orleans, Louisiana: October 2000

Medtronic Educational Grant (invited speaker) Neurosurgery + Science + Management Meeting New Orleans, Louisiana: October 2000

Robert Ginsberg Surgical Oncology Award by the Radiation Therapy Oncology Group (RTOG) 2008

Top Doc in America 2007, 2012-2013

Best Doctors in America ® 2007–2013

Cleveland Magazine Best Doctors 2012

 

Membership in Professional Societies
The College of Physicians and Surgeons of Ontario;1992 – Present

Royal College of Physicians and Surgeons of Canada; July 2001 – Present

American Association of Neurological Surgeons, Active Member; 2004 – Present

Congress of Neurological Surgeons; Active Member; 2004 – Present

Women in Neurosurgery: Active Member; 2005 – Present

 

Professional Services

Editorial Boards

Journal: Journal of Neurosurgery–Gamma Knife Edition

Dates of Service:  (2012)

 

Committee Service

National

Organization:  World Spine Column Society

Committee Name/Role:  Board Member-at-Large

Dates of Service:  July 2013 – Present

 

Teaching Activities

Curriculum/Course Development

Gamma Knife Radiosurgery 2004 Training Course:

Course Faculty & Speaker.  The Cleveland Clinic Foundation, Cleveland, OH: June 2004, Oct.  2004.

Gamma Knife Radiosurgery 2005 Training Courses:

Course Faculty & Speaker. The Cleveland Clinic Foundation, Cleveland, OH: April 2005, June 2005, Oct. 2005, Dec. 2005.

Gamma Knife Radiosurgery 2006 Training Courses:

Course Co-Director, Speaker & Hands –On Training Faculty. Cleveland Clinic, Cleveland, OH: Feb. 2006, April 2006, Aug. 2006,

Gamma Knife Radiosurgery 2007 Training Course:

Course Co-Director, Speaker & Hands – On Training Faculty Cleveland, OH:  Feb. 2007.

World Spine Society IV Congress: Session Moderator and Speaker “Spine Stereotactic Radiosurgery”. Istanbul, Turkey: Aug. 2007

Gamma Knife Radiosurgery 2008 Training Courses: Course Co-Director, Speaker & Hands-On Training Faculty. Cleveland Clinic, Cleveland, OH: Jan. 2008, June 2008, Aug. 2008, Dec. 2008.

Gamma Knife Radiosurgery 2009 Training Courses: Course Co-Director, Speaker & Hands–On Training Faculty. Cleveland Clinic, Cleveland, OH: April 2009, June 2009, Aug. 2009.

Gamma Knife Radiosurgery 2010 Training Courses: Course Co-Director, Speaker and Hands–On Training Faculty. Cleveland Clinic, Cleveland, OH: Jan. 2010, Oct. 2010, Dec. 2010.

Gamma Knife Radiosurgery 2011 Training Courses: Course Co-Director, Speaker and Hands–On Training Faculty. Cleveland Clinic, Cleveland, OH: Jan. 2011, Feb. 2011, March 2011, Aug. 2011, Oct. 2011, Nov. 2011

Gamma Knife Radiosurgery 2012 Training Courses: Course Co-Director, Speaker and Hands–On Training Faculty. Cleveland Clinic, Cleveland, OH: Jan. 2012, Aug. 2012, Oct. 2012, Dec. 2012.

Gamma Knife Radiosurgery 2013 Training Courses: Course Co-Director, Speaker and Hands–On Training Faculty. Cleveland Clinic, Cleveland, OH: Jan. 2013., March 2013, May 2013, Aug. 2013, Sept. 2013, Oct. 2013, Dec. 2013.

Gamma Knife Radiosurgery 2014 Training Courses: Course Co-Director, Speaker and Hands–On Training Faculty. Cleveland Clinic, Cleveland, OH: March 2014, May 2014, Dec. 2014.

Gamma Knife Radiosurgery 2015 Training Courses: Course Co-Director, Speaker and Hands-On Training Faculty. Cleveland Clinic, Cleveland OH: March, 2015, May 2015, Aug. 2015, Oct. 2015, Dec. 2015.

Spine Tumor Management Couse: Course Director and Speaker. “Introduction to Spine Tumors” and “Introduction to Radiosurgery”. Hyatt Regency Hotel, Cleveland OH: July 2015

Cleveland Spine Review-Hands-On 2015 Course: Course Director and Speaker: “Spinal Radiosurgery”. Cleveland Clinic Lutheran Hospital, Cleveland OH: July 2015

Gamma Knife Radiosurgery 2016 Training Courses: Course Co-Director, Speaker and Hands-On Training Faculty. Cleveland Clinic, Cleveland OH: April 2016, June 2016, Aug. 2016, Dec 2016.

Gamma Knife Center Radiosurgery Gamma Knife Perfexion Radiosurgery Training Program for CCF Physicians/Fellows/Residents. Speaker: “Normal radiation Tissue Tolerance and Radiosurgery for Benign Tumors”. Cleveland Clinic, Cleveland OH: July 7-8, 2016.

Brain Tumor/Radiosurgery Journal Club Activity Director. Cleveland Clinic, Cleveland OH: 2016

Department of Neurosurgery Visiting Professorship Activity Director. Cleveland Clinic, Cleveland OH: 2016

 

Presentations

  1. Royal College of Physicians and Surgeons Annual Meeting. Acute Myeloid Leukemia in First Relapse: Results of Therapy. Toronto, ON: Sept. 1990.
  1. Canadian Congress of Neurological Sciences. MRI and Spinal Cord and Column Injury. St. John’s, NFLD: June 1994.
  1. Canadian Congress of Neurological Sciences. Neurogenic Sarcomas: University of Toronto Experience. Victoria, BC: June 1995.
  1. Congress of Neurological Surgeons. Neurogenic Sarcomas:  The Toronto Experience. San Francisco, CA: Oct. 1995.
  1. American Association of Neurological Surgeons: Joint Section on Spine and Peripheral Nerves. University of    Toronto Sarcoma Group: Management of Neurogenic Sarcomas. Orlando, FL: March 1996.
  1. Ruth Jackson Visiting Professorship in Orthopedic Surgery at the University of Toronto. The Link Between Mitogenesis and Angiogenesis in NF-1. Toronto, ON: Jan. 1998.
  1. American Association of Neurological Surgeons. Reactive Astrocytes Express Vascular Endothelial Growth Factor (VEGF). Philadelphia, PA: April 1998.
  1. Institute of Medical Sciences, University of Toronto.  Vascular Endothelial Growth Factor Expression and Angiogenesis in Peripheral Nerve Lesions. Toronto, ON: April 1998.
  1. American Association for Cancer Research. Angiogenesis and Vascular Endothelial Growth Factor Expression in Peripheral Nerve Lesions. New Orleans, LO: April 1998.
  1. Canadian Congress of Neurological Sciences. Tumor Angiogenesis and VEGF Expression in Peripheral Nerve Lesions. Montreal, QUE: June 1998.
  1. Neurofibromatosis Society of Ontario. Advances in  Neurofibromatosis-1. Toronto, ON: Oct. 1998.
  1. The 1999 Keith Professorship in Neurosurgery. Biology and Pathogenesis of Peripheral Nerve Tumors. Toronto, ON: Feb. 1999.
  1. 1999 University of Toronto Surgical Oncology Day. VEGF and NF-1. Toronto, ON: Feb. 1999.
  1. Samuel Lunenfeld Research Institute Seminar Series. VEGF Expression and Receptor Inhibition in NF-1 Neurogenic Sarcomas. Toronto, ON: Feb. 1999.
  1. 1999 AACR Annual Meeting. VEGF Expression and Receptor Inhibition in Human Peripheral Nerve Tumors. Philadelphia, PA: April 1999.
  1. 1999 IMS Scientific Day Multidisciplinary Session in Hematology/Oncology. Modulating VEGF Mediated Angiogenesis in Human Peripheral Nerve Tumors. Toronto, ON: April 1999.
  1. 1999 AANS Annual Meeting. Increased Expression of Vascular Endothelial Growth Factor (VEGF) by Reactive Astrocytes in Associated with Cerebral Neoangiogenesis. New Orleans, LO: April1999.
  1. 1999 AANS Annual Meeting. Vascular Endothelial Growth Factor (VEGF) Expression and Receptor Inhibition in Peripheral Nerve Tumors. New Orleans, LO: April 1999.
  1. 2000 University of Toronto Division of Neurosurgery City Wide Rounds. Cerebellitis and HHV7 Infection. Toronto, ON: March 2000.
  1. Nerve Surgery of the New Millennium, A Symposium in Honor of Dr. Alan Hudson. Role of VEGF in Neurogenic Sarcomas. Toronto, ON: Sept. 2000.
  1. 2000 Neuroscience + Science + Management Meeting.  VEGF Expression and Antiangiogenic Therapy in Peripheral Nerve Tumors. New Orleans, LO: Oct. 2000.
  1. Neuro-Oncology 2003: Current Concepts Meeting. Temozolomide Therapy in the Management of Primary Central Nervous System Lymphomas. Orlando, FL: Jan. 2003.
  1. Neuro-Oncology 2004: Current Concepts Meeting. Session Moderator, Orlando, FL: Jan. 2004.
  1. Quarterly Neurology Section Meeting: Neurosurgical Management of Brain Metastasis. Lakewood Hospital, Lakewood, OH: Feb. 2004.
  1. Fundamental Critical Care Course: Cardiopulmonary/Cerebral Resuscitation Lecture. Lakewood Hospital, Lakewood, OH: March 2004.
  1. Lakewood Hospital Foundation’s Annual Meeting: Current Treatments in Neuroncology Union Club. Cleveland, OH: May 2004.
  1. Fairview Hospital Cancer Conference: Central Nervous System Metastasis. Fairview Hospital, Cleveland, OH: May 2004.
  1. Lakewood Hospital Grand Rounds: Current Treatment of CNS Metastatic Disease. Lakewood Hospital, Lakewood, OH: June 2004.
  1. Emergency Medicine Physicians Meeting: Updates on Neurosurgical and Neuro-Oncologic Emergencies.   Lakewood Hospital, Lakewood, OH: July 2004.
  1. Peripheral Markers of Blood Brain Barrier Failure III  Symposium: Molecular Markers of Brain Tumors. Speaker and Round Table Session Co-Moderator. The Cleveland Clinic Foundation, Cleveland, OH; Nov. 2004
  1. Neuro-Oncology 2005: Current Concepts Meeting Meningiomas: Review of Basic Sciences. Orlando, FL: Jan. 2005.
  1. Oregon Neurosurgical Society Quarterly Journal Club Meeting: Gamma Knife in Neurosurgical Disease. Portland,   OR March 2005
  1. Blood Brain Barrier Disruption Consortium Meeting: BBBD/IA Methotrexate Therapy for Primary CNS Lymphoma: The Cleveland Clinic Experience. Portland, OR, March 2005
  1. Fundamental Critical Care Course: Cardiopulmonary/ Cerebral Resuscitation Lecture. Fairview Hospital, Cleveland, OH: April 2005
  1. Neuro-Oncology Mini Symposium: Management of  Primary CNS Lymphoma: The Role of Blood Brain Barrier Disruption of Intra-Arterial Chemotherapy. The Cleveland Clinic Foundation. Cleveland, OH: Aug. 2005.
  1. 7th International Stereotactic Radiosurgery Society Congress: Poster Presentation: The Use if Tissue Equivalent Super Stuff Bolus ™ Material to Treat Skull Metastases with Gamma Knife Radiosurgery”. Brussels, Belgium: Sept. 2005.
  1. 2005 Congress of Neurological Surgeons Annual Meeting: Talk & Poster Presentation: Blood Brain Barrier Disruption and Intra-Arterial Methotrexate Therapy for Primary CNS Lymphoma: The Cleveland Clinic Experience. Boston, MA: Oct. 2005.
  1. 8th Annual Updates in Neuroscience Nursing. Speaker  Neuro-Oncologic Emergencies”. The Cleveland Clinic Foundation. Cleveland, OH: Nov. 2005.
  1. Neurosurgery Grand Rounds: Speaker, “Current Management of Primary CNS Lymphoma”. Cleveland Clinic. Cleveland, OH: Feb. 2006.
  1. General Surgery Interns Lecture. “Diagnosis and Management of Common Neurosurgical Emergencies”. Cleveland Clinic, Cleveland, OH: June 2006.
  1. 2006 Congress of Neurological Surgeons Annual Meeting: PC06 Spinal Radiosurgery Practical Course: Speaker & Poster Presentation. “Pain Improvements and Quality of Life Data”. Chicago, IL: Oct. 2006.
  1. Continuing Education Program Ambulatory Clinic Nursing and RN, LPN Lecture Series. Speaker “Gamma Knife Updates”. Cleveland Clinic, Cleveland OH: Nov. 2006. (Discussion)
  1. Moll Cancer Center Grand Rounds. Speaker “Novel Treatment Paradigms in the Management of Spinal Tumors”. Fairview Hospital, Fairview, OH: Jan. 2007.
  1. Neurosurgery Grand Rounds. Speaker “Spine Radiosurgery: A Novel Treatment Option”. Cleveland Clinic, Cleveland, OH:  Feb. 2007.
  1. International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery. Speaker, Moderator and Meeting Co-Director. Orlando, FL: Feb. 2007.
  1. Palliative Medicine Grand Rounds.  Speaker “Pain and the Role of Spine Radiosurgery”. Cleveland Clinic, Cleveland OH: March 2007.
  1. American Association of Neurological Surgeons 2007 Annual Meeting: Practical Clinic Spinal Radiosurgery. Speaker & Poster Presentation x 2. Washington, D.C.: April 2007.
  1. General Surgery Interns Lecture. “Diagnosis and Management of Common Neurosurgical Emergencies”. Cleveland Clinic, Cleveland, OH: April, 2007.
  1. American Society of Clinical Oncologists 2007 Annual  Meeting: Poster Discussion ID # 3829. Chicago, IL:  June 2007.
  1. Congress of  Neurological Surgeons Annual Meeting: Speaker “Spinal Radiosurgery”. San Diego, CA: Sept. 2007.
  1. Cleveland Clinic Brain Tumor and Neuro-Oncology Retreat: Speaker x 2 “Radiosurgery Cranial and Spinal”, “Lymphoma Program Update”.  Cleveland, OH: Sept. 2007.
  1. Cleveland Clinic Dept. of Occupational and Physical  Therapy Grand Rounds: Speaker “Brain Tumors and their Treatment”. Cleveland, OH: Oct. 2007.
  1. Regional Clinical Oncology Group: Speaker “Brain Tumors and their Treatment”. Independence, OH: Nov. 2007.
  1. Second Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery Meeting: Co-Director, Moderator Plenary Session I and Speaker “Spine Radiosurgery: Impact on Pain and Quality of Life”. Lake Buena Vista, FL: Feb. 2008.
  1. 5th Annual Neuroscience Centers of Excellence: Speaker “Optimizing a Neuro-Oncological Service Line Within a Neurosciences Center of Excellence Paradigm”. Orlando, FL: Feb. 2008.
  1. Cleveland Clinic Dept. of Neurosurgery Grand Rounds. Speaker “Management of PCNSL”: The International Blood Brain Barrier Disruption Experience. Cleveland, OH: Feb. 2008.
  1. Palliative Medicine – 12th Annual International Symposium: Speaker “Multidisciplinary Management of Spinal Metastatic Disease”. Scottsdale, AZ: March 2008.
  1. American Association of Neurological Surgeons Annual Meeting: Faculty Speaker “Pain and QOL Outcomes with Spine Radiosurgery”. Chicago, IL: April 2008.
  1. Fourth International Conference of the Novalis Circle Meeting: Chair of Scientific Session “Stereotactic Radiosurgery for Spine”, Speaker “Stereotactic Spine Radiosurgery (SRS) for Pain and Tumor Control in Patients with Spinal Metastases from Renal Cell Carcinoma: A Prospective Study”.  Session Moderator for “Spine Radiosurgery Workshop”.  Santa Barbara, CA: June. 2008.
  1. Cleveland Clinic Dept. of Palliative Medicine Grand Rounds: Speaker “Palliative Medicine and Neurosurgery–Interfacing to Create Effective Patient Care”. Cleveland Clinic, Cleveland OH: June 2008.
  1. Centro Medico Paitilla Scientific Meeting: Speaker x 2 “Treatment Options for Brain Metastases” and “Spine Radiosurgery: “A Novel Treatment Paradigm” Joint CC -:  Panama City, Panama: Jul. 2008.
  1. Managing Spine Tumors Symposium: Speaker “Relief and Quality of Life with Stereotactic Radiosurgery for Spine Tumors”. Cleveland, OH: July 2008.
  1. Yale Neurosurgery – Advances in Radiosurgery Course:  Speaker “Spine Radiosurgery”. Hartford, CT: Sept. 2008.
  1. Cleveland Clinic Neurology Grand Rounds: Speaker “Primary CNS Lymphoma: The Disease and Disrupting the Blood Brain Barrier to Treat it”. Cleveland, OH: Sept.2008.
  1. Cleveland Clinic International Center Mini Spine Symposium: Speaker and Case Study Workshop Session “Radiosurgery”. Cleveland, OH: Oct. 2008.
  1. Neuro-Oncology Symposium: Speaker “Radiosurgery for  Spinal Tumors”. Los Cabos, México: Nov. 2008.
  1. International Course: Speaker “Spinal Tumors”. Las Palmas, Spain: Nov. 2008.
  1. Metro Health Medical Center Tumor Board: Speaker “Spine Radiosurgery: Novel Minimally Invasive Management of Spine Tumors. Cleveland, OH: Dec. 2008.
  1. Cleveland Clinic Lerner College of Medicine Student Surgery Interest Group: Speaker, “Surgeons Specialties and Careers”. Cleveland, OH: Feb. 2009.
  1. Third Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery Meeting: Co-Director, Moderator Plenary Session I and Speaker “Spine Radiosurgery: Impact on Pain and Quality of Life”. Lake Buena Vista, FL: Feb 2009.
  1. Chongqing International Neurological Spine Radiosurgery Forum this was not the name of the forum: Speaker x 6 “A Novel Treatment for Spine Tumors”. Chongqing, China: March, 2009.
  1. Memorial Sloan-Kettering Cancer Center Spine Radiosurgery Consortium Participant “Spine Radiosurgery Workshop”. Manhattan, New York: March, 2009.
  1. Baptist Medical Center Neuroscience Symposium: Speaker – “Spine Radiosurgery: Prospective Assessment of Pain Improvement and Quality of Life”. Jacksonville, FL:  April 2009.
  1. American Association of Neurological Surgeons Annual Meeting: Faculty “Spine Radiosurgery Practical Course”. San Diego, CA: May 2009.
  1. World Federation Neurosurgical Societies Annual Meeting: Moderator “Metastatic Spine Cancer” &  General Session Moderator “Radiosurgery for Tumors 39”. Boston, MA: August, 2009.
  1. International Symposium Neuro-Oncology: Faculty: “Stereotactic Radiosurgery- What is the Best Management for Spine & Epidural Metastases”.  Cleveland, OH: September, 2009.
  1. American Association of Neurological Surgeons Resident Course on Stereotactic Radiosurgery: Faculty: “Quality of Life Spinal Radiosurgery Patients”. Charlottesville, VA: October, 2009.
  1. Congress of Neurological Surgeons Annual Meeting: Faculty & Speaker: “PC-31 Radiosurgery Update: Spinal” &“Stereotactic Radiosurgery Vertebroplasty & Kyphoplasty”. New Orleans, LA: October, 2009.
  1. American Society for Therapeutic Radiology & Oncology 2009 Annual Meeting: Faculty & Speaker:Spine Tumors: A Prospective Assessment of Spine Radiosurgery on Pain  and Quality of Life”. Chicago, IL: November, 2009.
  1. 12th Annual Innovations in Neuroscience Conference: Faculty & Speaker: “Radiosurgery- A Non-Surgical Approach”. Cleveland, OH: November, 2009.
  1. University of Calgary- Visiting Professor to the Division of Neurosurgery and the Department of Clinical Neurosciences. “Current Management Strategies for Primary Central Nervous system Lymphoma” & “Spinal Radiosurgery”. Calgary, Canada: December, 2009.
  1. American Association of Neurological Surgeons Annual Meeting: Faculty “Practical Clinic- Spinal Radiosurgery”.  Philadelphia, PA: May 2010.
  1. World Spine V & World Spine 2010 Hands on Course: Session Moderator & Speaker “Spine Radiosurgery as Part of a Multimodality Treatment for Spine Metastases” & “Spine Radiosurgery Principles and Outcomes”.  Santorini & Larissa Greece:  May 2010.
  1. International Symposium on Long-Term Control of Secondary Central Nervous System Malignancies: Symposium Director and Session Moderator “Minimizing the Impact of Spine Metastasis”.  Speaker “Radiosurgery and Vertebral Augmentation: When Less is More”. Cleveland, OH: June 2010.
  1. 5th International Conference of the Novalis Circle: Mini Course Chair & Platform Presentation.  Munich, Germany:  June 2010.
  1. 1st  International Brain Mets Symposium. Symposium Director & Speaker- “Radiosurgery and Vertebral Augmentation: When Less is More” & “Minimizing the Impact of Spine Metastasis”. Cleveland, OH: September 2010.
  1. American Association of Neurological Surgeons Stereotactic Radiosurgery Course for Residents: Course Co-Coordinator and Faculty- “Quality of Life in Radiosurgery Patients”. Cleveland, OH: September 2010.
  1. Congress of Neurological Surgeons Meeting: Faculty Speaker- “Spinal Oncology Update (Part 2): Radiosurgery & Adjuvant Therapies” & “Section on Disorders of the Spine & Peripheral Nerves- Management of Spinal Column  & Peripheral Nerve Neoplasms” & “State-of-the-Art in  Spinal Radiosurgery”. San Francisco, CA: October 2010.
  1. 9th Annual International Kidney Cancer Symposium: Speaker- “What is the Most Appropriate Local Treatment for Bone Metastases?-  Stereotactic XRT”. Chicago, IL:  October 2010.
  1. Stereotactic Body Radiotherapy Symposium: Lecture & Expert Speaker- “Stereotactic Body Radiotherapy for Spinal Tumors”. Amsterdam, Netherlands: January 2011.
  1. Fourth Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurger Meeting: Symposium Director, Moderator Plenary Session I I: Faculty Speaker- “Spine and Peripheral Nerve SRS”. Lake Buena Vista, FL: Feb 2011.
  1. American Association of Neurological Surgeons Annual Scientific Meeting: Faculty Speaker- “Update on Spinal Radiosurgery Practical Course”. Denver, CO: April 2011.
  1. International Stereotactic Radiosurgery Society Meeting: Platform Presentation-“Oral Session Spine II” & Faculty Speaker- “Radiosurgery as Part of a Multi-Modality Treatment for Spine Tumors”. Paris France: May 2011.
  1. International Symposium on Spine Tumor Innovations:  Course Director, Plenary Session Moderator & Speaker- “Introduction to Radiosurgery”. Cleveland, OH: July 2011.
  1. Cleveland Spine Review Course: Speaker-“Radiosurgery in the Spine”. Cleveland, OH: July 2011.
  1. 2nd International Brain Mets Symposium. Session Moderator & Speaker- “Radiosurgery and Vertebral Augmentation: When Less is More” & “Minimizing the Impact of Spine Metastasis”. Cleveland, OH: September 2011.
  1. Congress of Neurological Surgeons. Poster Presentation- “The Role of Gamma Knife Radiosurgery in Patients with Multiple (>=5) Brain Metastases” & “Patient Setup & Clinical Outcome”. Washington, DC: October 2011.
  1. Elekta Perfexion Innovations Meeting: Visiting Expert Professor Stockholm, Sweden: December 2011.
  1. Tenth Annual Caribbean Neurosciences Symposium Meeting. Speaker x 2- “Current Management of Brain Metastasis” & “Primary CNS Lymphoma”. Montego Bay Jamaica: January 2012.
  1. Fifth Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery Meeting: Symposium Director, Moderator Plenary Session I I: Faculty Speaker- “Combination Therapy for the Treatment of Spinal Metastases” Lake Buena Vista, FL:  February 2012.
  1. International Symposium on Spine Tumor Innovations: Course Director, Plenary Session Moderator & Speaker x 2-“Introduction to Spine Tumors” & “Introduction to Radiosurgery” Cleveland, OH: July 2012.
  1. Cleveland Spine Review Course: Speaker- “Spinal Radiosurgery as part of multimodality treatment”. Cleveland, OH: July 2012.
  1. Rio Brazil Meeting: Speaker- “Radiosurgery Spinal” & “Spinal Surgery and Spinal Radiosurgery Interactions”. Rio De Janeiro, Brazil: September 2012.
  1. Novalis Radiosurgery Symposium: Key Speaker- “Spinal Radiosurgery: A Revolution in the Management of Spinal Tumors”. Tel Aviv, Israel: January 2013.
  1. Sixth Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery Meeting: Symposium Director, Moderator: Spine SRS Session: Faculty Speaker- “Combination Therapy for the Treatment of Spinal Metastases” Lake Buena Vista, FL: February 2013.
  1. Cancer Institute Grand Rounds. Speaker “Spine Radiosurgery: Changing the Treatment Paradigm in Spinal Metastases”. Cleveland Clinic, Cleveland OH: April 2013
  1. ISRS 2013 Congress Meeting. Senior Author Platform Presentation: Session Chair “Predicting and Managing SBRT-induced VCF” & “Spine Physics 1” Oral Session Moderator. Toronto, Canada: June 2013.
  1. Cleveland Spine Review Course: Speaker – “Spinal Radiosurgery”.
     

Lutheran Hospital, Cleveland, OH: July 2013.

  1. Fifteenth Annual Brain Tumor Update and Fourth Annual International Symposium on Long-Term Control of Metastases to the Brain and Spine: Speaker – “Radiosurgery: Indications and Outcomes”. Bellagio Hotel, Las Vegas, NV: November 2013.
  1. First Qatar Neurosurgical Society Conference and Fourth Annual Congress of Gulf Neurosurgical Society: Keynote Lecture – “Radiosurgery for Brain Tumors including Metastasis”. Doha, Qatar: November 2013.
  1. First Qatar Neurosurgical Society Conference and Fourth Annual Congress of Gulf Neurosurgical Society: Speaker – “Radiosurgery for the Management of Spine Metastases – A New Tool in Our Tool Belt”. Doha, Qatar: November 2013.
  1. First Qatar Neurosurgical Society Conference and Fourth Annual Congress of Gulf Neurosurgical Society: Keynote Lecture – “Neuro-Oncology Emergencies”. Doha, Qatar: November 2013
  1. Seventh Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery Meeting: Symposium Director, Moderator: Spine SRS Session: Faculty Speaker- “Combination Therapy for the Treatment of Spinal Metastases”. Naples, FL: February 2014
  1. American Association of Neurological Surgeons Annual Scientific Meeting: Practical Clinic PC10: “Update on Spinal Radiosurgery” – Speaker: “Quality of Life Results”.


San Francisco, CA: April 2014.

  1. World Spine 6 and Cleveland Clinic Spine Review: Scientific Program Coordinator, Session Moderator “Tumors”. Speaker – “Introduction to Spine Radiosurgery”.


Montego Bay, Jamaica: May 2014

  1. Leksell Gamma Knife Society Seventeenth International Meeting: Moderator – “Spine Radiosurgery”. New York, NY: May 2014
  1. Sixteenth Annual Brain Tumor Symposium-Co-Director: Speaker: “Radiosurgery (Regular/Staged)” and “Building a Spine Radiosurgery Program”. Las Vegas, NV: November 2014
  1. Eighth Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery Meeting: Symposium Course Director; Moderator: “Spine SRS”. Lake Buena Vista, FL: February 2015
  1. Spine Oncology Symposium at Memorial Sloan Kettering Cancer Center: Speaker: “Quality of Life in Patients with Spine Tumors”. New York, NY: April 2015
  1. American Association of Neurological Surgeons/Congress of Neurological Surgeons Section on Tumors 11th Biennial Satellite Symposium: Speaker: “Quality of Life Results”. Washington, DC: May 2015
  1. International Stereotactic Radiosurgery Society Meeting: Oral Presentation – “Staged Stereotactic Radiosurgery Treatment on Large Brain Metastases Improves Local Control”, “Intracranial Metastases”, “Tumor Volume as a Predictor for Post-Stereotactic Radiosurgery Radiation Necrosis in Patients with Renal Cell Carcinoma Brain Metastasis that are >2cm. Yokohama, Japan: June 2015
  1. Second Scientific Conference of the North American Gamma Knife Consortium: Speaker: “Staged Radiosurgery Treatments for Brain Metastases”. Cleveland, OH: June 2015
  1. Spine Tumor Management: Course Director – Speaker: “Introduction to Spine Tumors” and “Introduction to Radiosurgery”. Hyatt Regency, Cleveland OH: July 2015
  1. 2015 Cleveland Spine Review Course: Speaker – “Spinal Radiosurgery”. Lutheran Hospital, Cleveland OH: July 2015
  1. Congress of Neurological Surgeons Annual Meeting, Novalis Circle Symposium presented by Brainlab: Speaker – “International Spine Radiosurgery Consortium Consensus Guidelines for Target Volume Definition in Spinal Stereotactic Radiosurgery”. New Orleans, LA: September 2015
  1. Seventeenth Annual Brain Tumor Update and Sixth Annual International Symposium on Long-Term Control of Metastases to the Brain and Spine – Co Director; Moderator: “Spinal Tumors and Metastases”. Speaker – “Spine Radiosurgery a Decade Later”; “Staged Gamma Knife Radiosurgery for the Treatment of Large Brain Metastases”. Las Vegas, NV: November 2015
  2. Ninth Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery Meeting: Symposium Course Director; Moderator: “Spine SRS”. Speaker – “Combination Therapy for the treatment of Spinal Metastases”. Orlando, FL: February 2016
  1. Indian Spine Injury Center Academic Meeting: Speaker – “SRS and Separation Surgery”. New Delhi, India: April 2016
  1. World Spine VII Meeting: Speaker – Luncheon Seminar: “Radiosurgery: What a Spinal Surgeon needs to know”; Chairperson: Spine Tumors Session; Speaker – “Stereotactic Radiosurgery for CV Junction Tumors”. New Delhi, India: April 2016
  1. American Association of Neurological Surgeons Annual Meeting: Speaker – “Update on Spinal Radiosurgery”; “Guidelines for Target Definition for Spine Radiosurgery”. Chicago, IL: April 2016
  1. Leksell Gamma Knife Society Meeting: Moderator: ‘Early Morning Seminiar #1: LINAC Radiosurgery Capabilities: Myth vs Reality’. Amsterdam, Netherlands: May 2016
  1. International Conference on Spine and Spinal Disorders: Speaker – “Spine Tumors: The Impact of Spine Radiosurgery on Pain and Quality of Life”; Session Chair: Spinal Cord Injury & Spine Tumors; Speaker – “Multimodality Management of Spine Tumors”. Valencia, Spain: June 2016
  1. Cleveland Spine Tumor Course: Symposium Chair; Speaker – “Introduction to Spine Tumors”; “Introduction to Radiosurgery”. Cleveland, OH: August 2016
  1. International Congress on Minimally Invasive Neurosurgery Meeting: Speaker – “Current Status of Radiosurgery within the Neurosurgical Practice”; “Spinal Radiosurgery Workshop Coordinator”. Cairo, Egypt: October 2016
  1. 7th Annual International Symposium on Long-Term Control of Metastases to the Brain and Spine: Speaker – “Spine Radiosurgery and Spine Separation”; “Staged Radiosurgery”. Las Vegas, NV: October 2016

 

Community Initiatives

Your Family’s Health Lakewood Hospital Community Publication. Article “The Right Place…The Right Time.” Winter 2006 Edition

Columbus James Cancer Center: Featured Support Group Speaker- Columbus, OH: October 2010

Neurological Institute Research Day. Judge for Platform Presentations. Cleveland, OH: May 2011

Kidney Cancer Association Patient & Survivors Meeting Speaker- “Management of Brain & Spine Metastasis”. Cleveland, OH: November 2011.

 

Visiting Professorships

  1. Ruth Jackson Visiting Professorship in Orthopedic Surgery at the University of Toronto.“The Link Between Mitogenesis and Angiogenesis in NF-1”, Toronto, ON, January 1998.
  1. University of Calgary, Visiting Professor to the Division of Neurosurgery and the Department of Clinical Neurosciences. “Current Management Strategies for Primary Central Nervous System”, Calgary, Canada, December 2009
  1. Elekta Perfexion Innovations Meeting: Visiting Expert Professor, Stockholm, Sweden, December 2011.
  1. National Center for Cancer Care and Research, Hamad Medical Corporation – Visiting Professor to the Department of Radiation Oncology, “The Role of Radiosurgery in the Management of CNS Metastases”, Doha Qatar, November 2013.

 

Research Support

  1. Co-Investigator – NABTT NIH Grant- Phase I/II Study of Novel Therapeutics for Brain Tumor Treatment.

 

  1. IRB 2559 Genetic and Molecular Analysis of Tumors of the Nervous System and their Coverings.

 

  1. IRB 6385 Phase II Clinical Trials of Patients with High-Grade Glioma Treated with Intra-Arterial Carboplatin-Based Chemotherapy, Randomized to Treatment with or without Delayed Intravenous Sodium Thiosulfate as a Potential Chemoprotectant Against Severe Thrombocytopenia.

 

  1. IRB 7791 RTOG 0320; A Phase III Trial Comparing Whole Brain Radiation and Stereotactic Radiosurgery Alone Versus With Temozolomide Or Gefitinib In Patients With Non-Small Cell Lung Cancer and 1-3 Brain Metastases.

 

  1. IRB 7992 Prospective Analysis of Wellness Following Gamma Knife for Non-Malignant Indications.

 

  1. IRB 8053 Phase II Trial of Motexafin Gadolinium with Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patient with Brain Metastases.

 

  1. IRB 8208 A Phase II Study of Temozolomide-Based Chemotherapy Regimen for High Risk Low-Grade Gliomas.

 

  1. IRB 3669 Protocol A: Combination Chemotherapy, Intraventricular Cytarabine & Methotrexate, +/- Intra-Ocular Chemotherapy for Patients with Primary Central Nervous System Lymphomas (PCNSL) & Protocol B: Combination Chemotherapy Delivered in Conjunction with Osmotic Blood-Brain Barrier Disruption (BBBD), with Intraventricular Cytarabine +/- Intra-Ocular Chemotherapy in Patients with Primary Central Nervous System Lymphoma (PCNSL).

 

  1. IRB 7982 Chart Review: Retrospective chart review of Blood Brain Barrier Disruption (BBBD/Intra-Arterial (IA) Chemotherapy in Primary Central Nervous System Lymphoma (PCNSL). Angelov, L. PI

 

  1. IRB 06-611 Chart Review: Evaluation of the Role of Gamma Knife Stereotactic Radiosurgery in Patients with Non-Small Cell Lung Cancer and Asymptomatic Intracranial Metastatic Disease. Angelov, L. PI

 

  1. IRB 8078 Prospective Study on the Short-Term Adverse Effects from Gamma Knife Radiosurgery.

 

  1. RTOG 0320: A Phase III Trial Comparing Whole Brain Radiation and Stereotactic Radiosurgery Alone Versus with Temozolomide or Gefitinib in Patients with Non-Small Cell Lung Cancer and 1-3 Brain Metastases.

 

  1. CC 038 A Phase I/II Study of Patients with Newly Diagnosed Primary Central Nervous System Lymphoma Treated with Methotrexate/BBBD, and Adding Rituximab (an anti-CD 20 Antibody) and Carboplatin, to the Treatment Regimen.

 

  1. CC 190 Phase I and II, Open-Label Multi-Center Trials Of Pazopanib in Combination With Lapatinib in Adult Patients with Relapsed Malignant Glioma.

 

  1. Blood Brain Barrier Disruption (BBBD) Consortium (Multi-Center) PCNSL Time to Progression Project. Angelov, L. PI

 

  1. IRB 07-692 The Impact of Treatment on Pain and Radiographic Tumor Control in Patients with Spinal Metastases Treated with Stereotactic Spine Radiosurgery (SRS). Angelov, L. PI

 

  1. IRB 09-553 Chart Review: Evaluation and Characterization of the Etiology of Spine Radiosurgery Failures. (active 7/6/2017) Angelov, L. PI

 

  1. IRB 09-829 Chart Review: The effects of conventional radiation Vs. Stereotactic Radiosurgery (SRS) on wound healing and bony fusion in spine surgery. (Angelov, L. PI)

 

  1. IRB 10-133 Chart Review: Evaluation of organs at risk during Radiation dosage delivered by Stereotactic Radiosurgery in Patients with Metastatic Cervico-thoracic Spinal disease. Angelov, L. PI

 

  1. IRB 06-972 Chart Review: Stereotactic Radiosurgery as Single Modality Treatment for Incidentally-Identified Renal Cell Carcinoma Brain Metastases. (Angelov, L. PI)

 

  1. IRB 07-267 Collection of Blood and Tissue from patients with Upper Aerodigestive Malignancies for research purposes (The UAM Tissue Resource).

 

  1. IRB 10-1056 Remifentanil Versus Dexmedetomidine- The Best Anesthetic Strategy For Craniotomy.

 

  1. IRB 11-478 Result of Gamma Knife Radio-surgery in patients with 5 or more Brain Metastases. (active 5/24/2017) Angelov, L. PI

 

  1. IRB 12-007 MONT 1311 Laser Ablation after Stereotactic Radiosurgery.

 

  1. IRB 12-123 N107C: A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease.

 

  1. IRB 12-197 An International, Multi-Center, Randomized, Double Blind Placebo Controlled Phase II Study to Evaluate the Safety and Efficacy of Lucanthone Administered as an Adjunct to Radiation and Temozolomide for Primary Therapy of Glioblastoma Multiforme.

 

  1. IRB 12-247 CLDX 1311: An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma.

 

  1. IRB 12-344 CASE 1312 A Phase 2 Evaluation of TRC105 in Combination with Bevacizumab for the Treatment of Recurrent or Progressive Glioblastoma Multiforme that has Progressed on Bevacizumab.

 

  1. IRB 12-940 DFCI 2312 An open-label, Phase 2 Trial of orally administered PF-0029804 in adult patients with relapsed/recurrent glioblastoma (GBM).

 

  1. IRB 13-221 Dose Escalation for Larger Brain Metastases: Phase I/II Study.

 

  1. IRB 13-530 CHART REVIEW The use of gamma knife stereotactic radiosurgery as salvage treatment for patients with recurrent glioblastoma at the Cleveland Clinic.

 

  1. IRB 13-1019 Medical Records: Stereotactic radiosurgery treatment of large brain metastases (metastases with maximal diameter>2cm).

 

  1. IRB 14-031 Medical Records: The Natural History of Pilocytic Astrocytoma in Adults: A Retrospective Analysis

 

  1. IRB 14-388 Effect of Gamma Knife Radiosurgery on Perilesional Edema Around Cerebellar Metastases.

 

  1. IRB CC 1009 ABTC0906 A Phase II and Pharmacodynamic Trial of RO4929097 for Patients with Recurrent/Progressive Glioblastoma.

 

  1. IRB 330 NBIO 1307: A Phase II Clinical Trial Evaluating DCVax-Brain, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme.

 

  1. IRB CC 578 ABTC#0703 Phase I / II study of the poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors BSI-201 in patients with newly diagnosed malignant glioma(NABTT).

 

  1. IRB 827 ABTC 0902 Phase I/II Study of Vorinostat (Suberoylanilide Hydroxamic Acid [SAHA]), Temozolomide, and radiation therapy in patients with newly diagnosed Glioblastoma.

 

  1. IRB CC 834 RTOG 0631 Phase II/III study of Imaging guided radiosurgery/SBRT for localized Spine Metastasis.

 

  1. IRB CC 879 EXEL 2310 A Phase I Dose Escalation Study of XL765 in combination with Temozolomide in subjects with malignant Gliomas (NCI).

 

  1. IRB CC00039 NCTG 1310: N0577 Phase III Intergroup Study of Radiotherapy versus Temozolomide Alone versus Radiotherapy with Concomitant and Adjuvant Temozolomide for Patients with 1p/19q Codeleted Anaplastic Glioma.

 

  1. IRB CC222 NABIT 0504: A Feasibility Assessment and Phase I/II Trial of MLN518 for Treatment of Patients with Recurrent Glioblastoma.

 

  1. IRB CC432 NABTT #0603 A Phase I/II Trial of Hydroxychloroquine In Conjunction with Radiation Therapy and Concurrent and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme.

 

  1. IRB CC603 CASE1308 Phase II Trial of Sunitinib as Maintenance Therapy after Stereotactic Radiosurgery in Patients with 1-3 Newly Diagnosed Brain Metastases.

 

  1. IRB 6860 Registry: Patients Treated with Radiotherapy Using the Novalis BrainLab System.

 

  1. IRB 07-574 Chart Review: Evaluation of the Role of Prior Surgical Resection/Stabilization on the Radiation dosage delivered by Stereotactic Radiosurgery in Patients with Metastatic Spinal Disease. (active 7/24/2017) Angelov L. PI

 

  1. IRB 09-553 Chart Review: Evaluation and Characterization of the Etiology of Spine Radiosurgery Failures (active 7/6/2017) Angelov L. PI

 

  1. IRB 2559 Genetic and Molecular Analysis of Tumors of the Nervous System and Their Coverings (active 6/30/2017) Angelov L. Co-Investigator

 

  1. IRB 15-1356 Medical Records: Fractal Dimensions as a tool for differentiation of radio necrosis from tumor progression (active 10/22/2016) Angelov L. PI

 

  1. IRB 15-1358 Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients with Extradural Spinal tumors – a Pilot Study (active 11/5/2017) Angelov, L. PI

 

  1. IRB 15-1028 Medical Records: Spinal Radiosurgery and single versus multiple levels. (active 8/13/2017) Angelov, L. PI

 

  1. IRB 16-859 Medical Records: Evaluation of Organs at Risk during Radiation Dosage Delivered by Stereotactic Radiosurgery in Patients with Metastatic Cervicothoracic Spinal disease. (active 6/30/2017) Angelov, L. PI

 

  1. IRB 16-674 Exempt: A survey of Spinal Stereotactic Radiotherapy in the United States.

Angelov, L. PI

 

 

Bibliography

Peer Reviewed Articles

  1. Angelov L, Brandwein J, Baker M, Scott J, Sutton D, Keating A. ”Results of Therapy for Acute Myeloid Leukemia in First Relapse”. Leukemia & Lymphoma. 6(1):15-24, 1991.

 

  1. Angelov L. “Marrow Miracle worker: E. Donnall Thomas”. University of Toronto Medical Journal. Vol 68(2):43, 1991.

 

  1. Laskin CA, Chuma A, Angelov L, Neil G, Levy GA, Mason N, Soloninka C, Cole E. “Sera from Habitual Aborters Induce Monocyte Procoagulant Activity: A Lymphocyte Dependent Event”. Clin Immunol Immunopath. 73(2): 235-44, 1994. PMID: 7923931

 

  1. Lala P, Angelov L, Provius J, Feldkamp MM, Guha “Growth Factors and Nervous System Tumors”. Adv Clin Neurosci. 6:245-289, 1996.

 

  1. Angelov L, Davis A, Bell RS, Guha A. “Management of Neurogenic Sarcomas: University of Toronto Experience”. Adv Clin Neurosci. 7:357-374, 1997.

 

  1. Angelov L, Davis A, O’Sullivan B, Bell RS, Guha A. ”Management of Neurogenic Sarcomas: University of Toronto Experience”. Neurosurg. 43:56-65, 1998. PMID: 9657189

 

  1. Feldkamp M, Angelov L, Guha A. “Neurofibromatosis Type 1 Peripheral Nerve Tumors: Aberrant Activation of the Ras pathway”. Surg Neurol. 51:211-218, 1999. PMID: 10029430

 

  1. Angelov L, Salhia B, Roncari L, McMahon G, Guha A. “Inhibition of Angiogenesis by Blocking Activation of the Vascular Endothelial Growth Factor Receptor 2 Leads to Decreased Growth of Neurogenic Sarcomas”. Cancer Res. 59:5536-5541, 1999. PMID: 10554031

 

  1. Angelov L, Salhia B, (co-first author) Roncari L, Wu X, Shannon P, Guha A. “Expression of Vascular Endothelial Growth Factor by Reactive Astrocytes and Associated Neoangiogensis”. Brain Res. 883:1987-97, 2000. PMID: 11063991

 

  1. Siomin V, Angelov L,  Li L, Vogelbaum M. “Results of a Survey of Neurosurgical Practice Patterns Regarding the Prophylactic Use of Anti-Epilepsy Drugs in Patients with Brain Tumors”. J Neuorooncol. 74(2):211-5, Sept 2005. PMID: 16193395

 

  1. Vogelbaum M, Angelov L, Lee S, Li L, Barnett G, Suh J. “Local control of Brain Metastases by Stereotactic Radiosurgery in Relation to Dose to the Tumor Margin”. Journal of Neurosurgery. 104(6): 907-912, June 2006. PMID: 16776334

 

  1. Angelov L. Stereotactic Spine Radiosurgery: A New Treatment Option for Spine Tumors. Cleveland Clinic Neuroscience Pathways, 2006.

 

  1. Marchi N, Angelov L, Masaryk T, Fazio V, Granata T Hernandez EO, Hallene K, Diglaw T, Franic L, Najm I, Janigro D. Seizure-Promoting Effect of Blood-Brain Barrier Disruption. 48 (4): 732-742, April 2007. PMID: 17319915

 

  1. 2005-2006 Cancer Program Annual Report: A Report of Fairview and Lakewood Hospitals. (Central Nervous System Tumors) 2007.

 

  1. Kruser T, Chao S, Elson P, Barnett G, Vogelbaum M, Angelov L, Weil R, Pelley R, Suh J. “Multidisciplinary Management of Colorectal Brain Metastases: A Retrospective Study”.   1;113(1):158-165, July 2008. PMID: 18459179

 

  1. Chao S, Barnett G, Vogelbaum M, Angelov L, Weil R, Neyman G, Reuther A, Suh J. Salvage Stereotactic Radiosurgery Effectively Treats Recurrences from Whole-Brain Radiation Therapy. Cancer. 15;113(8):2198-204, Oct. 2008. PMID: 18780319

 

  1. Kim SH, Weil RJ, Chao ST, Toms SA, Angelov L, Vogelbaum MA, Suh JH, Barnett GH. Stereotactic Radiosurgical Treatment of Brain Metastases in the Older Patient.                    Cancer.  113(4):834-40, 2008. PMID: 18536026

 

  1. Angelov L, Doolittle N, Kraemer D, Siegal T, Barnett G, Peereboom D, Stevens G, McGregor J, Jahnke K, Lacy C, Hedick N, Shalom E, Ference S, Bell, S, Soreson L, Tyson R, Haluska M, Neuwalt E. Blood-Brain Barrier Disruption and Intra-Arterial Methotrexate-Based Therapy for Newly Diagnosed Primary CNS Lymphoma: A Multi-Institutional Experience. J Clin Oncol, July 2009. PMID: 19451444

 

  1. Marko N, Angelov L, Toms S, Suh J, Chao S, Vogelbaum M, Barnett G, Weil R: “Stereotactic Radiosurgery as Single Modality Treatment for Incidentally-Identified Renal Cell Carcinoma Brain Metastases”. World Neurosurg. March 2010; 73(3):186-193. PMID: 20860956

 

  1. Prayson N, Angelov L, Prayson R: “Microscopic Thrombi in Glioblastoma Multiforme (GBM) Do Not Predict the Development of Deep Venous Thrombosis”. Ann Diagn Pathol. Oct 2009. PMID: 19751904

 

  1. Xu Z, Marko NF, Chao S, Angelov L, Vogelbaum M, Suh J, Barnett G, Weil R.  “Multi-Modality Therapy in Patients with Brain Metastases: Patients with HER2-Positive Breast Cancer have Improved Survival”.

 

  1. Koyfman S, Chao S, Vogelbaum, M, Angelov L, Weil R, Neyman G, Reddy C, Barnett G, Tendulkar R, Suh J. “Stereotactic Radiosurgery for Single Brain Stem Metastases”. Int Journal Radiation Oncology Biol Phys. 2010 Oct; 78(2):409-14.

 

  1. Angelov L, Bidros D, Djemil T, Neyman A, Chao S, Benzel E.“Surgical Separation: An Adjunctive Surgical Technique for Enhancing the Efficacy of Stereotactic Radiosurgery for Epidural Disease”.

 

  1. Harel R, Chao S, Krishnaney A, Emch T, Benzel E, Angelov L.“Spine Instrumentation Failure Following Spinal Tumor Resection and Radiation: Comparing Conventional Radiotherapy to Stereotactic Radiosurgery Outcomes”. World Neurosurgery. 2010 Oct;74(4-5):517-522. PMID: 21492605

 

  1. Ahluwalia M, Patton C, Stevens G, Tekautz T, Angelov L, Vogelbaum M, Weil R, Chao S, Elson P, Suh J, Barnett  G, Peereboom D: “Phase II Trial of Ritonavir/lopinavir in Patient with Progressive or Recurrent High-grade Gliomas”. J Neurooncol. 2011 Apr;102(2):317-21. Epub 2010 Aug 4. PMID: 20683757

 

  1. Prayson R, Chamberlain W, Angelov L: “Clear Cell Menningioma: A Clinicopathological Study of 18 Tumors and Examination of the Use of CD10, CA9 and RCC Antibodies to Distinguish Between Clear Cell Meningioma and Metastatic Clear Cell Renal Cell Carcinoma”. Appl Immunohistochem Mol Morphol. 2010 Oct;18(5):422-428.

 

  1. Koyfman S, Tendulkar R, Chao S, Vogelbaum M, Barnett G, Angelov L, Weil R, Neyman G, Reddy C, Suh J. “Stereotactic Radiosurgery for Single Brainstem Metastases”. The Cleveland Clinic Experience. Int J Radiation Oncology Biol Phys. 2010 Oct 1;78(2):409-414. PMID: 20133072

 

  1. Harel R, Angelov L. “Spine Metastases: Current Treatments and Future Directions”.

 Eur J Cancer. 2010 Oct; 46(15):2696-2707. PMID: 20627705

 

  1. Kshettry VR, Hardy S, Weil RJ, Angelov L, Barnett GH. “Immediate Titanium Cranioplasty after Debridement and Craniectomy for Post-Craniotomy Surgical Site Infection”. Neurosurgery. 2011 July 29. PMID: 21808217

 

  1. Marko N, Suh J, Chao S, Barnett GH, Vogelbaum M, Tom S, Weil R, Angelov L. “Gamma Knife Radiosurgery for the Management of Incidentally-Identified Brain Metastasis from Non-Small Cell Lung Cancer”. J Neurooncol. 2011 Sep;104(3):817-24. Epub 2011 Mar 23. PMID: 21431468

 

  1. Siomin V, Lin J, Barnett G, Vogelbaum, M, Chao S, Toms S, Angelov L, Suh J, Weil R, “Stereotactic Radiosurgical Treatment of Brain Metastases to the Choroid Plexus” . Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1134-1142. PMID: 21683888

 

  1. Bilsky MH, Angelov L, Rock J, Weaver J, Sheehan J,Rhines L, Azeem S, Gerszten. P. “Spinal Radiosurgery: a  neurosurgical perspective”. Journal of Radiosurgery and  SBRT. 47-54, 2011.

 

  1. Prayson N, Koch P, Angelov L, Prayson R. “Microscopic thrombi in anaplastic astrocytoma predict worse survival?” Ann Diagn Pathol. 2011 Dec;15(6):389-93. Epub 2011 Aug 16. PMID: 21849253

 

  1. Shin JH, Chao ST, Angelov L. “Stereotactic Radiosurgery for Spinal Metastases Update on Treatment Strategies”. J Neurosurg Sci. 2011 Sep;55(3):197-209.

 

  1. Sahgal A, Ma L, Weinberg V, Gibbs IC, Chao S, Chang U, Werner-Wasik M, Angelov L, Chang E, Sohn M, Soltys S, Letourneau D, Ryu S, Gerszten P, Fowler J, Wong C, Larson D.  “Reirradiation human spinal cord tolerance for stereotactic body radiotherapy”. Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):107-116.  PMID:  20951503

 

  1. Kshettry V, Hardy S, Weil R, Angelov L, Barnett G. “Immediate titanium cranioplasty after debridement and craniectomy for postcraniotomy surgical site infection”. Neurosurgery. 2012 Mar;70 (1 Suppl Operative):8-15. PMID: 22343833

 

  1. Xu Z, Marko NF, Angelov L, Barnett GH, Chao ST, Vogelbaum MA, Suh JH, Weil RJ.  Impact of preexisting  tumor necrosis on the efficacy of stereotactic radiosurgery in the treatment of brain metastases in women w cancer. Cancer. 2012 Mar 1;118(5):1323-1333. PMID: 22009460

 

  1. Chao S, Koyfman S, Woody N, Angelov L, Soeder S, Reddy C, Rybicki L, Djemil T, Suh J.  “Recursive partitioning analysis index is predictive for overall survival in patients undergoing spine stereotactic body radiation therapy for spinal metastases”. Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1738-1743. PMID: 21489717

 

  1. Xu Z, Marko N, Chao S, Angelov L, Vogelbaum MA, Suh J, Barnett G, Weil R.  “Relationship between HER2 status    and prognosis in women with brain metastases from breast cancer”. Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):e739-e747. PMID: 22024205

 

  1. Chao S, Thakkar V, Barnett G, Vogelbaum M, Angelov L, Weil R, Rasmussen P, Reuther A, Jamison B, Neyman G, Suh J. “Prospective Study of the Short-Term Adverse Effects of Gamma Knife Radiosurgery”. Technol Cancer Res Treat. 2012 Apr;11(2):117-122. PMID: 22335405

 

  1. Koyfman S, Djemil T, Burdick M, Woody N, Balagamwala E, Reddy C, Angelov L, Suh J, Chao S.  “Marginal recurrence requiring salvage radiotherapy after stereotactic body radiotherapy for spinal metastases”. Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):297-302. PMID 21985940

 

  1. Hunter G, Suh J, Reuther A, Vogelbaum M, Barnett G, Angelov L, Weil R, Neyman G, Chao S.  “Treatment of five or more brain metastases with stereotactic radiosurgery”. Int J Radiat Oncol Biol Phys. 2012 Aug 1;83(5):1394-1398. PMID: 22209150

 

  1. Balagamwala E, Cherian S, Angelov L, Suh J, Djemil T, Lo S, Sahgal A, Chang E, Teh B, Chao S.  “Stereotactic body radiotherapy for the treatment of spinal metastases”. J Radiat Oncol. 2012 Sep;1(3):255-265.

 

  1. Hunter GK, Balagamwala EH, Koyfman SA, Bledsoe T, Sheplan LJ, Reddy CA, Chao ST, Djemil T, Angelov L, Videtic GM. “The efficacy of external beam radiotherapy and stereotactic body radiotherapy for painful spinal metastas4es from renal cell carcinoma”. Pract Radiat Oncol. 2012 Oct-Dec;2(4):395-e100. PMID: 24674192

 

  1. Balagamwala E, Angelov L, Koyfman S, Suh J, Reddy C, Djemil T, Hunter G, Xia P, Chao S.  “Single-fraction stereotactic body radiotherapy for spinal metastases from renal cell carcinoma”. J Neurosurg Spine. 2012 Dec;17(6):556-564. PMID: 23020208

 

  1. Mohammadi A, Recinos P, Barnett G, Weil R, Vogelbaum M, Chao S, Suh J, Marko N, Elson P, Neyman G, Angelov L.  “Role of Gamma Knife surgery in patients with 5 or more brain metastases”. J Neurosurg . 2012 Dec;117 Suppl:5-12. PMID:23205782

 

  1. Sahgal A, Weinberg V, Ma L, Chang E, Chao S, Muacevic A, Gorgulho A, Soltys S, Gerszten P, Ryu S, Angelov L, Gibbs I, Wong C, Larson D. “Probabilities of Radiation Myelopathy Specific to Stereotactic Body Radiation Therapy to Guide Safe Practice”. Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):341-347. PMID: 22713832

 

  1. Sahgal A, Atenafu EG, Chao S, Al-Omair A, Boehling N, Balagamwala EH, Cunha M, Thibault I, Angelov L, Brown P, Suh J, Rhines LD, Fehlings MG, Chang E. “Vertebral compression fracture after spine stereotactic body radiotherapy: a multi-institutional analysis with a focus on radiation dose and the spinal instability neoplastic score”. J Clin Oncol. 2013 Sep 20;31(27):3426-31 PMID: 23960179

 

  1. Kshettry VR, Angelov L. “Technical note regarding immediate titanium mesh cranioplasty for postcraniotomy infections.” World Neurosurg. 2014 Mar-Apr;81(3-4):e16. PMID: 24017952

 

  1. Shiue K, Barnett GH, Suh JH, Vogelbaum MA, Reddy CA, Weil RJ, Angelov L, Neyman G, Chao ST. “Using higher isodose lines for gamma knife treatment of 1 to 3 brain metastases is safe and effective”. Neurosurgery. 2014 Apr;74(4):360-4; discussion 364-5; quiz 365-6. PMID: 24448185

 

 

  1. Mohammadi AM, Sullivan TB, Barnett GH, Recinos V, Angelov L, Kamian K, Vogelbaum MA. “Use of high-field intraoperative magnetic resonance imaging to enhance the extent of resection of enhancing and nonenhancing gliomas”. Neurosurgery. 2014 April;74(4):339-48; discussion 349; quiz 349-50. PMID: 2436854

 

  1. Seastone DJ, Elson P, Garcia JA, Chao ST, Suh JH, Angelov L, Rini BI. “Clinical outcome of stereotactic radiosurgery for central nervous system metastases from renal cell carcinoma”. Clin Genitourin Cancer. 2014 Apr;12(2):111-6. PMID: 24331575

 

  1. Ahmed Z, Balagamwala E, Murphy E, Angelov L, Suh J, Lo S, Chao S. “Postoperative stereotactic radiosurgery for resected brain metastasis”. CNS Oncol. 2014 May;3(3):199-207. PMID: 25055128

 

  1. Healy AT, Otvos B, Schroeder J, Hamrahian AH, Angelov L, Kamian K. “Hurthle cell carcinoma presenting as a single choroid plexus metastasis”. J Clin Neurosci. 2014 Aug;21(8):1448-50. PMID: 24656751

 

  1. Mohammadi AM, Sullivan TB, Barnett GH, Recinos V, Angelov L, Kamian K, Vogelbaum MA. “Use of high-field intraoperative magnetic resonance imaging to enhance the extent of resection of enhancing and nonenhancing gliomas”. Neurosurgery. 2014 Apr;74(4):339-48. PMID: 24368543

 

  1. Grabowski MM, Recinos PF, Nowacki AS, Schroeder JL, Angelov L, Barnett GH, Vogelbaum MA. “Residual tumor volume versus extent of resection: predictors of survival after surgery for glioblastoma”. J Neurosurg. 2014 Nov; 121(5):1115-23. doi: 10.3171/2014.7.JNS132449. Epub 2014 Sep 5. PMID: 25192475

 

  1. Kotecha R, Angelov L, Barnett GH, Reddy CA, Suh JH, Murphy ES, Neyman G, Chao ST”. “Calvarial and skull base metastases: expanding the clinical utility of Gamma Knife Surgery”. J Neurosurg. 2014 Dec;121 Suppl:91-101. PMID: 25434942.

 

  1. Zimmerman AL, Murphy ES, Suh JH, Vogelbaum MA, Barnett GH, Angelov L, Ahluwalia M, Reddy CAf, Chao ST. “Treatment of large brain metastases with stereotactic radiosurgery”. Technol Cancer Res Treat. 2015 Jan 28. pii: [Epub ahead of print] PMID: 25633136.

 

  1. Hsieh J, Elson P, Otvos B, Rose J, Loftus C, Rahmathulla G, Angelov L, Barnett GH, Weil RJ, Vogelbaum MA. “Tumor progression in patients receiving adjuvant whole-brain radiotherapy vs localized radiotherapy after surgical resection of brain metastases”. 2015 Apr;76(4):411-20. PMID: 25599198

 

  1. Kotecha R, Zimmerman A, Murphy ES, Ahmed Z, Ahluwalia MS, Suh JH, Reddy CA, Angelov L, Vogelbaum MA, Barnett GH, Chao ST. “Management of brain metastasis in patients with pulmonary neuroendocrine carcinomas”. Technol Cancer Res Treatment. 2015 June 3. pii: 1533034615589033. [Epub ahead of print] PMID: 26041398.

 

 

  1. Ahluwalia MS, Chao St, Parsons MW, Suh JH, Wang D, Mikkelsen T, Brewer DJ, Smolenski KN, Schilero C, Rump M, Elson P, Angelov L, Barnett GH, Vogelbaum MA, Weil RJ, Peereboom DM. “Phase II trial of sunitinib as adjuvant therapy after stereotactic radiosurgery in patients with 1-3 newly diagnosed brain metastases”. J Neurooncol. 2015 Sep;124(3):485-91. doi: 10.1007/s11060-015-1862. Epub 2015 Aug 6. PMID: 26245136

 

  1. Harel R, Emch T, Chao S, Elson P, Krishnaney A, Djemil T, Suh J, Angelov L. “Quantitative Evaluation of Local Control and Wound Healing Following Surgery and Stereotactic Spine Radiosurgery (SRS) for Spine Tumors”. World Neurosurg. 2016 Mar;87:48-54. doi: 10.1016/j.wneu.2015.10.075. Epub 2015 Nov 5. PMID: 26548834

 

  1. Murphy ES, Chao ST, Angelov L, Vogelbaum MA, Barnett G, Jung E, Recinos VR, Mohammadi A, Suh JH. “Radiosurgery for pediatric brain tumors”. Pediatric Blood Cancer. 2016 Mar;63(3):398-405. doi: 10.1002/pbc.25831. Epub 2015 Nov 4. PMID: 26536284

 

  1. Mohammadi AM, Schroeder JL, Angelov L, Chao ST, Murphy ES, Yu JS, Neyman G, Jia X, Suh JH, Barnett GH, Vogelbaum MA. “Impact of the radiosurgery prescription dose on the local control of small (2cm or smaller) brain metastases”. J Neurosurg. 2016 May 27:1-9. [Epub ahead of print] PMID: 27231978

 

  1. Silva D, Grabowski MM, Juthani R, Sharma M, Angelov L, Vogelbaum MA, Chao S, Suh J, Mohammadi A, Barnett GH. “Gamma Knife radiosurgery for intracranial hemangioblastoma”. J Clin Neurosci. 2016 Sep;31:147-51. doi: 10.1016/j.jocn.2016.03.008 Epub 2016 Jul 13. PMID: 27422585

 

  1. Miller JA, Bennett EE, Xiao R, Kotecha R, Chao ST, Vogelbaum MA, Barnett GH, Angelov L, Murphy E, Yu J, Ahluwalia M, Suh JH, Mohammadi AM. “Association Between Radiation Necrosis and Tumor Biology Following Stereotactic Radiosurgery for Brain Metastasis”. 2016 Aug;63 Suppl 1:196-7. doi: 10.1227/01.neu.oooo489820.05971.e1. PMID 27399529

 

  1. Miller JA, Balagamwala EH, Angelov L, Suh JH, Rini B, Garcia JA, Ahluwalia M, Chao ST. “Spine stereotactic radiosurgery with concurrent tyrosine kinase inhibitors for metastatic renal cell carcinoma”. J Neurosurg Spine. 2016 Jul 8:1-9. [Epub ahead of print] PMID: 27391397

 

  1. Jung EW, Jung DL, Balagamwala EH, Angelov L, Suh JH, Djemil T, Magnelli A, Chao ST. “Single-Fraction Spine Stereotactic Body Radiation Therapy for the Treatment of Chordoma”. Technol Cancer Res Treat. 2016 Jun 3. Pii: 1533034616652775. [Epub ahead of print] PMID: 27260562

 

  1. Miller JA, Balagamwala EH, Angelov L, Suh JH, Djemil T, Magnelli A, Qi P, Zhuang T, Godley A, Chao ST. “Stereotactic Radiosurgery for the Treatment of Primary and Metastatic Spinal Sarcomas”. Technol Cancer Res Treat. 2016 Apr 12. Pii: 1533034616643221. [Epub ahead of print] PMID: 27074915

 

  1. Harel R, Emch T, Chao S, Elson P, Krishnaney A, Djemil T, Suh J, Angelov L. “Quantitative Evaluation of Local Control and Wound Healing Following Surgery and Stereotactic Spine Radiosurgery for Spine Tumors”. World Neurosurg. 2016 Mar;87:48-54. doi: 10.1016/j.wneu.2015.10.075. Epub 2015 Nov 5. PMID: 26548834

 

 

  1. Kotecha R, Zimmerman A, Murphy ES, Ahmed Z, Ahluwalia MS, suh JH, Reddy CA, Angelov L, Vogelbaum MA, Barnett GH, Chao ST. “Management of Brain Metastasis in Patients With Pulmonary Neuroendocrine Carcinomas”. Tech Cancer Res Treat. 2016 Aug;15(4):566-72. doi: 10.1177/1533034615589033. Epub 2015 June 3. PMID: 26041398

 

  1. Zimmerman AL, Murphy ES, Suh JH, Vogelbaum MA, Barnett GH, Angelov L, Ahluwalia M, Reddy CA, Chao ST.”Treatment of Large Brain Metastases With Stereotactic Radiosurgery”. Technol Cancer Res Treat. 2016 Feb;15(1):186-95. doi: 10.1177/1533034614568097. Epub 2015 Jan 28. PMID: 25633136

 

  1. Miller JA, Balagamwala EH, Chao ST, Emch T, Suh JH, Djemil T, Angelov L. “Spine Stereotactic Radiosurgery for the treatment of multiple myeloma”. J Neurosurg Spine. 2016 Oct 28:1-9. [Epub ahead of print] PMID: 27791828

 

  1. Balagamwala EH, Miller JA, Angelov L, Suh JH, Mohammadi AM, Djemil T, Magnelli A, Soeder S, Chao ST. “Clinical and Quality of life Implications of Vertebral Compression Fracture Following Spine Radiosurgery”. Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2S):E132. doi: 10.1016/j.ijrobp.2016.06.923 PMID: 27673861

 

  1. Kotecha R, Vogel S, Suh JH, Barnett GH, Murphy ES, Reddy CA, Parsons M, Vogelbaum MA, Angelov L, Mohammadi AM, Stevens GH, Peereboom DM, Ahluwalia MS, Chao ST. “A Cure is Possible: A Study of 10-year Survivors of Brain Metastases”.

J Neurooncol. 2016 Sep;129(3):545-55. doi: 10.1007/s11060-016-2208-8. Epub 2016

Jul 25. PMID: 27456950

 

  1. Sharma M, Bennett Ee, Rahmathulla G, Chao ST, Koech HK, Gregory SN, Emch T, Magnelli A, Meola A, Suh JH, Angelov L. “Impact of cervicothoracic region stereotactic spine radiosurgery on adjacent organs at risk”. Neurosurg Focus. 2017 Jan;42(1):E14. doi: 10.3171/2016.10.FOCUS16364. PMID: 28041323 (Cover article)

 

  1. Bennett EE, Berriochoa C, Habboub G, Brigeman S, Chao ST, Angelov L. “Rapid and complete radiological resolution of an intradural cervical cord lung cancer metastasis treated with spinal stereotactic radiosurgery: case report”. Neurosurg Focus.

2017 Jan;42(1):E10. doi: 10.3171/2016.9.FOCUS16254. PMID: 28041319

 

  1. Miller JA, Kotecha R, Ahluwalia MS, Mohammadi AM, Suh JH, Barnett GH, Murphy ES, Vogelbaum MA, Angelov L, Chao ST. “The impact of tumor biology on survival and response to radiation therapy among patients with non-small cell lung cancer brain metastases”. Practical Radiation Oncology. 2017 Jan 5. Pii: S1879-8500(17)30001-2. doi: 10.1016/j.prro.2017.01.001 Epub ahead of print] PMID: 28254368

 

  1. Miller JA, Kotecha R, Ahluwalia MS, Mohammadi AM, Chao ST, Barnett GH, Murphy ES, Vogelbaum MA, Angelov L, Peereboom DM, Suh JH. “Overall survival and the response to radiation therapy among molecular subtypes of breast cancer brain metastases treated with targeted therapies”. Cancer. 2017 Feb 3. doi: 10.1002/cncr.30616. [Epub ahead of print] PMID: 28192598

 

 

 

  1. Kotecha R, Miller JA, Venur VA, Mohammadi AM, Chao ST, Suh JH, Barnett GH, Murphy ES, Funchain P, Yu JS, Vogelbaum MA, Angelov L, Ahluwalia MS. “Melanoma brain metastasis: The impact of stereotactic radiosurgery, molecular profile and targeted/immune-based therapies on treatment outcome”. Journal of Neurosurgery. Accepted for Publication. 2017 Jan 26.

 

 

Book Chapters (published or in press only)

  1. Lala P, Angelov L, Provius J, Guha A. Growth Factors in Nervous System Tumors. In: Cancer of the Nervous System: (McLBlack P, Loeffler J, eds), Blackwell Publishing, chapter 39:744-772: Boston 1997.

 

  1. Angelov L, Saunders R, Guha A. Peripheral Nerve Tumors. In: Contemporary Neurosurgery: (Tindall G, ed.): 2000.

 

  1. Angelov L, Feldkamp MM, Guha A. Management of Peripheral Nerve Tumors. In: Operative Neurosurgery: (Kaye, AH, McLBlack P, ed.). Harcourt Publishers Ltd., chapter 174:2155-2167: London 2000.

 

  1. Feldkamp MM, Angelov L, Gutmann D, Guha, A. Neurogenetics of Peripheral Nerve Tumors. In: Textbook of Tumors of the CNS, Spinal Axis, Skull Base and Peripheral Nerves (Berger M, ed.): 2000.

 

  1. Angelov L, Guha A. Peripheral Nerve Tumors. In: Neuro-Oncology the Essentials (Bernstein M, Berger MS, eds). Thieme Medical Publishers, Inc., chapter 43:434-444: New York 2000.

 

  1. Prayson RA, Angelov L, Barnett GH. Mixed Neuronal-Glial Tumors. In: Textbook of Neuro-Oncology (Berger, MS, Prados, M.D. eds). Elsevier Saunders, chapter 30:222-226: Philadelphia 2005.

 

  1. Angelov L, Barnett, G.H. Awake Craniotomy and Intra-op Imaging. In:  Image Guided Surgery (Barnett GH, Maciunas RJ, Roberts DW eds). Computer-Assisted Neurosurgery: Taylor & Francis: 2006.

 

  1. Angelov L, Golubic M. Molecular basis of Meningioma Tumorgenesis and Progression. (Lee J, ed.) Mengiomas:  Diagnosis, Treatment, and Outcome © Springer   Pp 147-156, Verlag London Limited 2008.

 

  1. Angelov L. Spine Radiosurgery: Pain and Quality of Life Outcomes. Shaped Beam Radiosurgery, Part III, Chapter 20. Springer Heidelberg.

 

  1. Rini B, Angelov L: Nonsystemic Approach to the Management of Metastatic Renal Cell Carcinoma. Renal Cancer- Emerging Cancer Therapeutics. Stadler W (ed). New York, NY: Demos Medical. Volume 2, Issue 1: Page 89: 2011.

 

  1. Angelov L. “Tech, Complication & Management” Evidence Based Neurosurgery- Third Edition. 2011.

 

  1. Angelov L: Spine Radiosurgery: Pain and Quality of Life Outcomes. Shaped Beam Radiosurgery. De Salles A (ed). London, NY: Springer. Chapter 20: 2011.

 

  1. Shin J, Angelov L:  Stereotactic Radiosurgery for the Treatment of Spinal Metastases. Spine Surgery. Benzel EC (ed). Philadelphia: Elsevier/Saunders. Chapter 176: 2012.

 

  1. Harel R, Angelov L: Metastatic Tumors of the Spine. The Evidence for Neurosurgery. Ghogawala Z (ed). Shrewsbury, UK: Castle Hill Barns. Chapter 10: 2012.

 

  1. Bilsky M, Angelov L: Stereotaxic Radiosurgery for Spine Tumors. The Cervical Spine. Benzel EC (ed). Philadelphia, PA: Lippincott Williams & Wilkins. Chapter 56: 2012.

 

  1. Angelov L, Chao S, Suh JH: Clinical Outcomes of Pain and Quality of Life after Spinal Radiosurgery. Spine Radiosurgery (2nd Edition); Gerszten P, Ryu S (ed). Thieme Medical Publishers, New York NY. Chapter 13: 2015.

 

  1. Angelov L, Mille J, Balagamwala E, Chao ST, Emch, T, Suh J, Djemil, T. “Spine Stereotactic Radiosurgery for the Treatment of Multiple Myeloma”.

 

Audio/Video/CD-Rom, etc.

  1. Invited Section Lecture in Cleveland Clinic Wellness Institute “Stress Free Now for Healers Program” Video Initiative: The Goal of Empathy and Compassion 2014 (accredited for AMA PRA Category 1 Credit)
  1. Cleveland Clinic Live Web Chat. Stereotactic Spine Radiosurgery: “A Unique Treatment Option for Spine Tumors”, May 2009
  1. MSNBC Live Interview discussing Brain Tumors. Re: Senator Edward Kennedy’s Diagnosis, June 2008
  1. Web interview with ABC discussing Malignant Gliomas. Re: Senator Edward Kennedy’s Diagnosis, June 2008
  1. Medical Miracles – WKYC Channel 3. October 2005
  1. The Learning Channel Medical Video Series. “The Operation – Back Microsurgery” AV#87854. 1993
  1. Consult QD Case Study Spotlights – Cleveland Clinic: “Pioneering Use of Staged Radiosurgery for Previously Untreatable Brain Metastases. A profile of multidisciplinary metastasis management”. November 2015
  1. Consult QD/Neurosciences – Cleveland Clinic: “Pioneering Staged Gamma Knife Therapy for Large Brain Metastases”. December 5, 2016

 

Abstracts

  1. Angelov L, Brandwein J, Scott J, Sutton D, Baker M, Keating. Factors Predicting Outcome of Chemotherapy for Acute Myeloid Leukemia (AML) in First Relapse. Clin Invest Med 13(4) Suppl B:B45: 1990.
  1. Angelov L, Mikulus D, Fehlings M. Evaluation of Spinal Column and Spinal Cord Injuries by Magnetic Resonance Imaging. Can J Neurol Sci 21(Supp 2):S25: 1994
  1. Angelov L, Davis A, Bell R, Guha A. Neurogenic Sarcomas: Experience of the University of Toronto. Can J Neurol Sci 22(Supp 1):S64: 1995.
  1. Angelov L, Roncari L, Guha A. Vascular Endothelial Growth Factor (VEGF) Expression and Angiogenesis in Peripheral Nerve Tumors. J Neuro-Oncol 39(3): 1998.
  1. Angelov L., Salhia B, Roncari L, McMahon G, Shawver L, Guha A. Vascular Endothelial Growth Factor (VEGF) Expression and receptor Inhibition in Human Peripheral Nerve Tumors. Proceedings of the American Association for Cancer Research 40:1515, 1999.
  1. Angelov L, Lee S-Y, Barnett G, Suh J, Vogelbaum M. Tumor Margin Dose Affects Local Control in Patients with Metastatic Brain Tumors Treated with Gamma Knife Stereotactic Radiosurgery. CNS Annual Meeting 806: 2003.
  1. Angelov L, Lee S-Y, Barnett G, Suh J, Vogelbaum M. The Response to Treatment of Melanoma Brain Metastasis with Stereotactic Radiosurgery Alone or in Combination with Whole Brain Radiation Therapy. CNS Annual Meeting: 2003.
  1. Vogelbaum M, Angelov L, Siomin V, Lee S-Y, Li L. Results of a Survey of Neurosurgical Practice Patterns Regarding the Prophylactic Use of Anti-Epilepsy Drugs in Patients with Brain Tumors. CNS Annual Meeting: 2004.
  1. Angelov L, Peereboom D, Stevens G, Sorenson L, Ference S, Vogelbaum M, Toms S, Barnett G. Blood Brain Barrier Disruption and Intra-Arterial Methotrexate Therapy for Primary CNS Lymphoma: The Cleveland Clinic Experience. #142; 2005 CNS Annual Meeting: 2005.
  1. Chao S, Barnett G, Angelov, L Toms S, Vogelbaum M, Neyman G, Katz E, Reuther, A. and Suh J. Salvage Stereotactic Radiosurgery Effectively Treats Recurrences from Whole Brain Radiation Therapy. ASTRO: Denver, CO: 2005.
  1. Marchi N, Angelov L, Masaryk T, Najm I, Fazio V, Grananta T, Janigro D. Seizure Promoting Effect of Human Blood Brain Barrier Disruption. European Epilepsy Meeting. Helsinki, Finland: June 2006.
  1. Marchi N, Angelov L, Masaryk T, Najm I, Fazio V, Grananta T, Janigro D. Seizure Promoting Effect of Human Blood Brain Barrier Disruption. #2006-A-2999-SfN, Society for Neuroscience, Atlanta, GA: Oct.2006.
  1. Angelov L. Blood Brain Barrier Disruption (BBBD) and Intra-Arterial Methotrexate Based Therapy for Newly Diagnosed Primary CNS Lymphoma: The BBBD Consortium Experience. #31829 ASCO Annual Meeting:  2007.
  1. Angelov L, Suh J, Ference Sandy, Sorenson L, Djemil T, Mahadevan A, Chao S.  Spine Tumors:  The Impact of Spine Radiosurgery on Pan and Quality of Life.  CNS #167 Section on Tumors Select Abstract  Session: Sept. 2007.
  1. Anna Neyman, John Suh, Jorge A. Garcia, Brian I. Rini, Ronald Bukowski,  Daniel Heng,  Bryson Borg, Paul Elson, and Lilyana Angelov. “Effective Pain and Tumor Control Using Stereotactic Radiosurgery (SRS) for the Treatment of Renal Cell Carcinoma Spinal Metastases.”  Kidney Cancer Association: Chicago II: Oct. 2007.
  1. Chao S, Thakkar V, Jamison B, Reuther A, Barnett G, Vogelbaum M, Angelov L, Toms S, Neyman G, Suh J.  Prospective Study on the Short-term Adverse Effects from Gamma Knife Radiosurgery.  ASTRO:  Los Angeles, CA:  Nov. 2007.
  1. Kruser T, Chao S, Elson P, Barnett G, Vogelbaum M, Toms S, Angelov L, Suh J. Multidisciplinary Management of Colorectal Cancer Brain Metastases: A Retrospective Study. ASTRO: Los Angeles, CA. Nov. 2007.
  1. Suh J, Neyman A, Elson P, Chao S, Vogelbaum M, Angelov L, Barnett G. Results of Stereotactic for Brain Metastases from Breast Cancer. ASTRO: Los Angeles, CA. Nov. 2007.
  1. Chao S, Kruser T, Elson P, Barnet G, Vogelbaum M, Tom S, Angelov L, Suh J, “Multidisciplinary Management of Brain Metastases from a Colorectal Cancer”: Retrospective Study. ASTRO: Los Angeles, CA. Nov. 2007.
  1. Djemil T, Mahadevan A, Gajdos S, Suh J, Lieberman I, Angelov L, Vedula B, Levine L. “Localization and Tracking of Lesions in Bony Anatomy Using the Calypso 4D Localization System”.  ASTRO: Los Angeles, CA. Nov. 2007.
  1. Heng D, Neyman A, Suh J, Garcia J, Rini B, Bukowski R, Borg B,  Angelov L. “Prospective Study of Stereotactic Radiosurgery (SRS) for Pain and Tumor  Control in Patient with Renal Cell Carcinoma (RCC) and Spinal Metastases”. ASCO GU, San Francisco, CA: Feb 2008.
  1. Chamberlain W, Angelov L, Prayson R. “Use of CD10, CA9 and RCC to Distinguish Between Clear Cell Meningioma and Metastactic Clear Cell Renal Cell Carcinoma”. Mod Pathol 2008; 21 (Suppl 1):319A.
  1. Barnett G, Neyman G, Suh J, Angelov L, Braun D, Chao S, Vogelbaum M, Weber P, Weil R.  Cleveland Clinic Experience with Gamma  Knife Perfexion for Benign Tumors.                      14th International  Meeting of the Leksell Gamma Knife ® Society: Quebec, Canada: May 2008.
  1. Kraemer D, Angelov L, Doolittle N, Siegel T, Peereboom D, Jahnke K, Bell S, Barnett G, McGregor J,  Neuwalt E. “The Importance of Total Dose Intensity in the Treatment of Primary Central Nervous System. ASCO:  Chicago, IL: June 2008.
  1. Kraemer D, Angelov L, Doolittle N, Siegel T, Peereboom D, Jahnke K, Bell S, Barnett G, McGregor J, Neuwalt E. “Degree of Blood Brain Barrier Disruption and Cumulative Total Dose Intensity in the Treatment of Primary Central Nervous System Lymphoma. European Association of Neuro-Oncology: Barcelona, Spain: Sept. 2008.
  1. Chao S, Elson P, Angelov L, Vogelbaum M, Barnett G, Videtic G, Mekhail T. Suh J. “New Classification Scheme to Predict Survival in Patients with Brain Metastases from Non-Small Cell Lung Cancer Treated with Upfront Stereotactic Radiosurgery” ASTRO: Boston, MA: Sept. 2008.
  1. Peterson C, Suh J, Angelov L, Reddy C, Chao S. “Survival and Prognostic Factors for Patients Diagnosed with Central Nervous System Radiation Changes by Pathology Specimen”: Retrospective Analysis. ASTRO: Boston, MA: Sept. 2008.
  1. Koyfman S, Tendulkar R, Chao S, Vogelbaum M, Barnett G, Angelov L, Weil R, Neyman G, Reddy C, Suh J. “Gamma Knife Radiosurgery for Single Brain Stem Metastases”. The Cleveland Clinic Experience. ASTRO: Boston, MA: Sept. 2008.
  1. Angelov L, Chao S, Heng D.Y., Djemil T, Kolar M, Suh J, “Stereotactic Spine Radiosurgery (SRS) for Pain and Tumor Control in Patients with Spinal Metastases from Renal Cell Carcinoma”: A Prospective Study. ASTRO:  Boston, MA:  Sept. 2008.
  1. Angelov L, Neyman A, Chao S, Suh J, Djemil T, Elson P, “Spine Tumors: A Prospective Assessment of Spine Radiosurgery on Pain and Quality of Life” ASTRO: Chicago, IL: Nov. 2009.
  1. Hunter G, Suh J, Vogelbaum M, Barnett G, Angelov L, Weil R, Reuther A, Neyman G, Chao S, “Treatment of Five or More Brain Metastases with Stereotactic Radiosurgery (SRS)”  ASTRO: Chicago, IL: Nov. 2009.
  1. Marina O, Angelov L, Djemil T, Suh J, Chao S, “Outcome after Single-fraction Stereotactic Radiosurgery (SRS) for Lumbar and Sacral Tumors of the Spine”. ASTRO: Chicago IL: Nov 2009.
  1. Seastone D, Elson P, Chao S, Angelov L, Rini B. “Clinical Outcome of Gamma Knife (GK) Radiotherapy for Central Nervous System (CNS) Metastases from Renal Cell Carcinoma (RCC)”. ASCO: Chicago, IL: June 2010.
  1. Rahmathulla G, Djemil T, Chao S, Emch T, Angelov L. “Impact of Cervico-Thoracic Region Spine Radiosurgery on Adjacent Organs at Risk”  ASTRO: San Diego, CA: April 2010.
  1. Mohammadi A, Weil R, Chao S, Marko N, Barnett G, Vogelbaum M, Suh J, Neyman G, Angelov L. “The Role of Gamma Knife Radiosurgery in Patients with Multiple (>=5) Brain Metastases” CNS: Washington, DC: October 2011.
  1. Mohammadi A, Weil R, Chao S, Marko N, Barnett G, Vogelbaum M, Suh J, Neyman G, Angelov L. “The Role of Gamma Knife Radiosurgery in Patients with Multiple (>=5) Brain Metastases” CNS: Washington, DC: October 2011.
  1. Mohammadi A, Chao S, Rini B, Garcia J, Suh J, Angelov L. “The role of stereotactic radio-surgery in the treatment of renal cell carcinoma patients with ≥5 brain metastases”. #89038 ASCO-GU: San Francisco, CA: February 2012.
  1. Djemil T, Qi P, Tizora N, Angelov L, Chao S. “Dosimetric Effect Of Rotation On Stereotactic Body Radiotherapy (SBRT) Of The Spine”: American Association of Physicists in Medicine (AAPM): Charlotte, NC: July 2012.
  1. Djemil T, Ouzidane M, Unal S, Reddy C, Angelov L, Suh J, Chao S. “Dosimetric Effect of Implanted Hardware in Spine SBRT: Comparison of the Actual Planning Dose Using Pencil Beam Calculation to Monte Carlo” submitted ASTRO: Boston, MA: October 2012.
  1. Chi M, Venur VA, Mohammadi AM, Chao ST, Budd GT, Montero AJ, Moore HF, Elson P, Suh JH, Angelov L, Barnett, GH, Abraham J, Ahluwalia MS. Graded prognostic assessment (GPA) of HER2 positive breast cancer patients with brain metastases. ASCO 2015 Annual Meeting, Chicago IL. May 29-June 2, 2015
  1. Abbassy M, Angelov L. “Staged Stereotactic Radiosurgery Treatment on Large Brain Metastases Improves Local Control” and “Tumor Volume as a Predictor for Post-Stereotactic Radiosurgery Radiation Necrosis in Patients with Renal Cell Carcinoma Brain Metastasis that are >2 cm. 12th International Stereotactic Radiosurgery Society Congress: Yokohama, Japan: June 2015
  1. Kotecha R, Krishnan S, Suh JH, Murphy ES, Reddy CA, Barnett GH, Vogelbaum MA, Angelov L, Mohammadi A, Stevens G, Peereboom D, Ahluwalia MS, Chao ST. Is there an Optimal Cost-Effective Method of Treating Patients with Limited Brain Metastases? North American Gamma Knife Consortium Meeting. Cleveland, OH. June 27-28, 2015
  1. Kotecha R, Venur VA, Murphy ES, YU J, Chao ST, Suh JH, Elson P, Angelov L, Barnett GH, Ahluwalia MS. Impact of BRAF Mutation on Outcome Following Stereotactic Radiosurgery in Melanoma Brain Metastases. ASTRO 2015 Annual Meeting. San Antonio TX. October 18-21, 2015
  1. Patel, K, Kotecha R, Ahluwalia MS, Suh JH, Reddy CA, Barnett GH, Vogelbaum MA, Angelov L, Murphy ES, Chao ST. Patients with Brain Metastases Treated Across Two Decades: Times Change But Does Survival Stay the Same? ASTRO 2015 Annual Meeting. San Antonio TX. October 18-21, 2015
  1. Kotecka R, Krishnan S, Suh JH, Murphy ED, Reddy CA Barnett GH, Vogelbaum MA, Angelov L, Mohammadi A, Stevens G, Peereboom D, Ahluwalia MS, Chao ST. Determining the Optimal Management of Patients with Limited Brain Metastases: A Cost Analysis Approach. ASTRO 2015 Annual Meeting. San Antonio, TX. October 18-21, 2015
  1. Kotecha R, Suh JH, Barnett GH, Murphy ED, Reddy CA, Parsons M, Vogelbaum MA, Angelov L, Mohammadi A, Stevens G, Peereboom D, Ahluwalia MS, Chao ST. A Cure is Possible: A Study of 10-Year Survivors of Brain Metastases. ASTRO 2015 Annual Meeting. San Antonio, TX. October 18-21, 2015
  1. Berriochoa C, Bennett E, Miller J, Balagamwala E, Ward M, Chao ST, Suh J, Benzel E, Soeder S, Yu N, Manyam B, Angelov L. A Comparison of Oncologic and Toxicity Outcomes in Patients Receiving Conventional External Beam Radiotherapy versus SBRT to Instrumented Spinal Fields. ASTRO 2016 Annual Meeting in Boston MA.

September 25-28, 2016.

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